Pethidine and General Anaesthesia

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Circulatory effects of pentazocine and pethidine during general anaesthesia with nitrous oxide, oxygen and halothane.

Pentazocine 30 mg and pethidine 30 mg were given intravenously to two groups of patients receiving general anaesthesia with nitrous oxide, oxygen and halothane. The injections were repeated after 10 minutes. The effects on cardiac output, arterial blood pressure, heart rate and central venous pressure were measured. Both drugs caused a transient fall (approximately 20 per cent) in cardiac outpu...

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Pethidine is indicated for the treatment of moderate to severe pain, and is delivered as its hydrochloride salt in tablets, as a syrup, or by intramuscular or intravenous injection. For much of the 20th century, pethidine was the opioid of choice for many physicians; in 1983 60% of doctors prescribed it for acute pain and 22% for chronic severe pain. Compared to morphine, pethidine was supposed...

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Pethidine is indicated for the treatment of moderate to severe pain, and is delivered as its hydrochloride salt in tablets, as a syrup, or by intramuscular or intravenous injection. For much of the 20th century, pethidine was the opioid of choice for many physicians; in 1983 60% of doctors prescribed it for acute pain and 22% for chronic severe pain. Compared to morphine, pethidine was supposed...

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ژورنال

عنوان ژورنال: BMJ

سال: 1951

ISSN: 0959-8138,1468-5833

DOI: 10.1136/bmj.2.4737.943